it was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (ap). it seems that some other types of mechanisms must be involved in ap propagation. in this article, we...

abstract background: understanding the electrophysiological effects of toxins, may facilitate new drugs discovery. buthotusschach (bs) has been shown to be one of the most dangerous scorpions in tropical part of iran. present study was aimed to investigate the electrophysiological effects of two active fractions (f4 and f6) isolated from bs scorpion toxin on action potential (ap) characteristic...

ion channels are responsible for control of cell function in excitable tissues such as heart and brain and also in organs and tissues traditionally thought to be non- excitable including liver and epithelium. in the present research, the effect of lead (pb2+) on ca2+ -dependent action potential and currents was studied in f77 neuronal soma membrane of helix aspersa. for this purpose, action pot...

an integrated model for magnetoencephalography (meg) and functional magnetic resonance imaging (fmri) is proposed. in the proposed model, meg and fmri outputs are related to the corresponding aspects of neural activities in a voxel. post synaptic potentials (psps) and action potentials (aps) are two main signals generated by neural activities. in the model, both of meg and fmri are related to t...

compound action potential (cap) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. these properties are measured using amplitude, latency and area under curve of caps recorded from spinal cord. here, the isolated spinal cord was set in a double sucrose gap (dsg) chamber and its response to intracellular stimulation ...

introduction: some dental sealers have neurotoxic effects on neuronaltissues. these effects appear to be mediated through the inhibition of ionic channels. intracellular recording was performed on neuronal cells tocharacterize the underlying ionic mechanisms of neurotoxicity induced by roth 801. materials and methods: experiments were carried out on f1 neuronal soma membrane located in the righ...

It was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. Some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (AP). It seems that some other types of mechanisms must be involved in AP propagation. In this article, we...

Glossary activation a term referring to the time-and voltage-dependent growth of a membrane conductance after membrane depolarization all-or-nothing a term that refers to the property that action potentials, if they occur, have a stereotyped shape that is largely independent of the size and form of the suprathreshold stimulus current clamp an experimental protocol in which transmembrane current...

It was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. Some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (AP). It seems that some other types of mechanisms must be involved in AP propagation. In this article, we...